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Lonicerae japonicae Flos is the dry buds of the Lonicera japonica Thunb.which is mainly distributed in Shandong,Henan and Hebei and other areas in China.More and more reports have shown that caffeoylquinic acids have a definite anti-bacterial activity and have been used for the treatment of hepatitis,H1N1 influenza virus,HIV and HIV-related symptoms.