Owing to the remarkable progress in the last two decades in supramolecular chemistry,one can now design and tailor a variety of beautiful nanostructures by optimizing a thermodynamic control.This has indeed contributed to the vast advancement of nanosciences.However,there still remains an essential missing link between molecular/nano structures and those with meso/macroscopic size regimes.This is mainly because the assembling events from “nanoscale size regimes” toward “upper hierarchical levels” suffer from an irreversible interference by numerous kinetic traps,leading to the formation of ill-defined macroscopic structures.Obviously,this missing link is one of the major reasons why nanosciences have not yet been integrated well into practical applications.Looking at our body,one could readily recognize that many biological events rely on certain functions of soft materials with an elaborate macroscopic structural anisotropy.One may also understand that the biological formation of such soft anisotropic structures often makes use of physical perturbations,e.g.,electrical potentials,ion/fluid fluxes,osmotic pressures,and sheer forces,so that the assembling events can be properly guided without being interfered by kinetic traps.Here we report our recent achievements related to this fundamental issue in the fields of supramolecular polymerization1 and materials science.References.