The receptor for advanced glycation end products is required for β-catenin stabilization in a chemic

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:sunapplesun
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  目的 The receptor for advanced glycation end products (RAGE) belongs to one of the pattern-recognition receptors (PRRs) expressed in the airway epithelium,which provides a molecular platform for the recognition of ligand complexes and amplication of immune responses.Recently,it has been identified to be fundamental to the process of allergic sensitization and the progression of allergen-induced pulmonary inflammation.However,the mechanisms involved are largely unknown.
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