Breast cancer is the most frequent cancer in women.Incidences rate are high most in the developed countries with very favourable survival.Annual incidence is increasing of 3% in Asia withsurvival rates of 57% compared to 73%in developed countries.Lower survival believed to be caused by advanced stage at presentation that usually found in Asia countries.Although tumor size, nodal status and grade remained the most important prognostic factors for long term survival, the role of mitotic index, LVI, Her2-positivity, gene profiling, comorbidity, age, BRCA mutations and socioeconomic status were also importantly considered.Some studies showed that breast cancer in Asia found in younger ages compared to western countries and BRCA2 mutation mostly found in some countries.This study presented some clinicopathological characteristics and BRCA mutations of breast cancer in some Asia countries and the possibility of their survival influence of breast cancer in Asia.