Plasmatic Levels Od Angiogenetic and Immunosupressive Factors TGF Betal, VEGF and Antitumor Cellular

来源 :2013第六届世界癌症大会 | 被引量 : 0次 | 上传用户:l342016022
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  In view of the fact that defects in immune response often correlate with poor prognosis, research in recent years has focused on the task of precisely describing the status and function of the immune system in cancer patients.It also appears that factor contributing to the poor immune defence agains tumor could be transforming factor-beta (TGF-beta).This is a highly immunosuppressive factor that inhibits the natural and specific immunity against tumors and stimulates the production of VEGF.We monitor immune responses in patients with colorectal cancer and breast cancer resistant to hormone therapy.
其他文献
Patients with neuroblastoma due to N-Myc oncogene-amplification die of tumour metastasis.However, little is known about how N-Myc induces cell migration, invasion and metastasis.The histone demethylas
会议
MicroRNAs (miRNAs) regulate tumor progression and invasion via direct interaction with target messenger RNAs (mRNAs).We defined miRNAs involved in cancer metastasis (metastamirs) using an established
会议
The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis, and motility in human cancer cells.We aim to elucidate the function of
会议
The non-classical HLA class I antigen HLA-G has been suggested to be part of strategies for tumor cells to avoid from host immunosurveillance.Aberrant HLA-G expression was frequently detected in metas
会议
Human papillomavirus (HPV) is associated with different malignancies but its role in the pathogenesis of ovarian cancer is controversial.This study investigated the possible role of human papillomavir
会议
Biobank is a type of biorepository that stores biological samples for use in research.It plays a major role in prognosis, diagnosis and treatment of human diseases.The development of translational med
会议
Imatinib (Gleevec(R), Glivec(R)), a selective inhibitor of ABL, KIT, and PDGFRA/B, is the first line targeted therapy for gastrointestinal stromal tumor (GIST).Unfortunately, the median-progressionfre
会议
1.Background: Personalized Medicine requires tools that allow to investigate the expression of molecular markers, in particular of signal transduction cascades, on the single-cell level to understand
会议
Resistance and recurrence of breast cancer following initial successful endocrine treatment is of major clinical concern.Screening for drug treatment efficacy in vitro requires reliable measurement of
会议
Objective: Establishing patient-derived subrenal capsule (SRC) xenografls in pancreatic cancer (PC) as a novel pre-clinical model for predicting chemotherapeutic responsiveness.Methods: 24 PC patients
会议