黑蒜对链脲佐菌素糖尿病大鼠的降血糖研究

来源 :中国生物工程学会第六次全国会员代表大会暨第九届学术年会 | 被引量 : 0次 | 上传用户:wxsshj
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目的:研究“黑蒜”(Black garlic)对链脲佐菌素致实验性糖尿病大鼠体质量与血糖的影响,并初步探讨其作用机理. 方法:腹腔注射50mg/kg链脲佐菌素造大鼠糖尿病模型.模型大鼠连续灌胃黑蒜30天,测定灌胃前及30天灌胃结束后大鼠体质量与血糖值. 结果:剂量为10g/kg的黑蒜对正常大鼠体质量和血糖水平没有显著的影响;对实验性糖尿病大鼠高、中(10g/kg、5g/kg)剂量组与模型对照组大鼠比较体质量均持续下降,血糖值持续升高,其差异无统计学意义.低剂量组(2.5g/kg)与模型对照组大鼠比较体质量下降有所缓解,血糖值升高慢于模型对照组,其差异具有统计学意义. 结论:适量食用黑蒜有降低血糖值、延缓糖尿病发展的作用,其机制尚需进一步研究.
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