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Some dinoflagellate species within genus Alexandrium, Gymnodinium and Pyrodinium have been known as important producers of paralytic shellfish toxins (PSTs), especially A.tamarense and A.catenella.PSTs could be accumulated in filtering-feeding bivalves when exposed to toxic algae, and toxin profiles and content in bivalves could be related to the species and density of toxic species in seawater.In.2011, samples of scallop Patinopecten yessoensis were collected from northern Yellow Sea and the toxins in different tissues (including mantle, digestive gland, adductor muscle, and gonad) were analyzed PSTs by high-performance liquid chromatography coupled with fluorescence detector (HPLC-FLD).The results showed that PST content in the digestive gland was the highest, followed by the mantle, gonad and the adductor muscle and.The high potency carbamate toxins occupy the maximum content proportion (about 79.6%) in the mantle, but the digestive gland was dominated by the low potency N-sulfocarbamoyl toxins (contributing from 57% to 71.8%, average 65.9%).The major PSTs presented in the digestive gland were C 1/2 and B 1 (GTX5), following by moderate amount of GTX2/3, and trace quantities of STXs.Based on the toxin profile in the digestive gland, it was suggested that A.tamarense and/or A.catenella could be the source of PSTs in Patinopecten yessoensis from northern Yellow Sea.