大自然广博深奥,人类对其进行的探索和认知永无止境.近年来,我们通过分子开关和智能响应功能材料的研究,不断加深对部分自然奥秘的领悟,首先发现缺陷态引起的电子旋风现象,有望对深入理解植物光合作用中叶绿体如何高效将水分解成为氧气和质子的机制提供启示;首次展示了力与酸碱度改变和分子间链式质子转移的关联,为在分子层面上深入理解触觉神经电信号传导提供了新思路;首次将电致自由基离子作为原位酸碱用于光电显示,同时
Over the past several decades,radical chemistry has been at the forefront of research in organic synthesis due to its generally mild reaction conditions,high functional group tolerance and unique sele
H-phosphonates play a major role in the research and application of the organic phosphorus chemistry[1].
A novel and efficient method to construct the pyrazolo[5,1-a]isoindole scaffold1-3 via a one-pot three-component cascade reaction of 1-(2-bromophenyl)buta-2,3-dien-1-one with hydrazine and isocyanide
An efficient protocol for synthesis of benzofulvene derivatives from easily available diarylacetylenes has been developed.
The indole skeleton and indole-containing polycyclic compounds,which constitute the core structure of numerous alkaloid and natural molecules,show distinct biological and pharmaceutical activity.
Heterocycles such as chromans and chromenes are important classes of benzopyran derivatives to be found in many natural products and synthetic molecules exhibiting unique biological and pharmacologica
Being aromatic substrates and possessing masked functional groups of alkene,diene,enol ether,or 1,4-diketone,furan derivative which can be obtained sustainably from biomass is a particularlyattractive
In our continuing search for safe and efficacious antifilarial drug,a series of novel chalcone-benzothiazole hybrids have been synthesized and evaluated for their Brugia malayi thymidylate kinase(BmTM
Coumarin compounds have attracted considerable attention in medicinal chemistry due to their extensively biological activities such as antibacterial,antifungal,antiviral,anticoagulant,anti-inflammator