【摘 要】
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Parkinsons disease (PD) is a common age-related degenerative disease of the central nervous system caused by hereditary, pesticides, metals, and polychlorinated biphenyls.Paraquat (PQ), a widely used
【机 构】
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Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment factors and Cance
【出 处】
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2016中国毒理学会神经毒理专业委员会学术年会
论文部分内容阅读
Parkinsons disease (PD) is a common age-related degenerative disease of the central nervous system caused by hereditary, pesticides, metals, and polychlorinated biphenyls.Paraquat (PQ), a widely used herbicide, causes PD.Long noncoding RNAs (lncRNAs) are nonprotein-coding transcripts,expressed in the brain and play irreplaceable roles in neurodegenerative diseases.Nrf2 is an important genetic transcription regulator in oxidative stress.We aimed to discover novel PQ or MPTP-Nrf2-related lncRNAs and explore their associations with PD.
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