We synthesized a series of multi-functional T1 magnetic resonance (MR) imaging contrast agents for targeted multi-modality imaging.Firstly, monodisperse silica-coated Mn3O4 nanoparticles (NPs) were sy
Estrogens (1) play crucial roles in the normal physiology of a variety of tissues.The actions of estrogens are mediated by the estrogen receptors (ER α/β), which function as ligand-regulated transcrip
Anti-angiogenesis is an effective strategy for cancer treatment because uncontrolled tumor growth depends on tumor angiogenesis and sufficient blood supply.Thus, blocking angiogenesis could be a strat
Cellular thiols-containing biomolecules, such as cysteine (Cys), homocysteine (Hcy), glutathione (GSH), and cysteine proteases, are significantly associated with a wide variety of cancer progressions.
As one of the biologically significant reactive oxygen species (ROS), hypochlorous acid (HOCl) plays a vital role in host innate immunity and has effective antibacterial properties.However, oxidative
Compound 1 was synthesized as a fluorescence sensor for Hg2+, the binding process was indicated by a distinct "off-on" fluorescent changes.All the results showed that, in the 1-Hg2+ complex, a sandwic
The phosphate sensor in aqueous solution, 1, is synthetized by 4-amino-1, 8-naphthalimide, oxalyl chloride and methanol.It shows sensitive and selective response to PO43-in DMSO-HEPES (0.02M, PH=7.4,