Discovery and Characterization of 5-HT Receptors and Transporters in HeLaS3 Cells by [3H]8-OH-DPAT a

来源 :2011第四届世界癌症大会 | 被引量 : 0次 | 上传用户:abc1234Shi
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  Some G protein-coupled receptors (GPCRs) have functional links to cancer biology, yet the manifestation of GPCRs in tumor types is little studied to date.Using a battery of radioligand binding assays for profiling GPCR targets on HeLaS3 cells; high level of specific binding of a 5-HT1A receptor recognition binding agonist [3H]8-OH-DPAT was observed in these cells and characterized.
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