A series of novel 3-(2,4-dihydroxyphenyl)-propionic acid amides were synthesized and evaluated as tyrosinase inhibitors using a tyrosinase-dependent tyrosine oxidation assay.
Azole rings are an important class of unusual poly-nitrogen aromatic heterocycles able to readily interact with various biological cations,anions,small molecules and macromolecules such as DNAs,enzyme
Bacterial resistance has become a serious threat to human health.Research to discover antibacterial agents with novel mechanisms of action is of great importance.In this study,eleven series of chalcon