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目的调查南昌地区健康成年男性骨密度,探讨吸烟与骨密度的关系。方法采用法国MEDILINK公司生产的型号为OSTEOCORE2双能X线骨密度仪测量548例南昌地区健康成年男性正位腰椎(L2~L4)、左侧股骨颈及左前臂BMD,分析不同年龄组BMD及骨质疏松患病率变化。并根据吸烟指数进行分组,分析BMD与吸烟指数关系。结果正位腰椎、股骨颈、前臂BMD峰值均出现在30~39岁年龄段,而后随年龄增加而下降,50岁以后降低更明显,骨质疏松患病率均随年龄增加而增加。吸烟指数与正位腰椎BMD呈负相关(r=-0.472,P﹤0.01),与股骨颈、前臂BMD呈弱负相关(r值分别为-0.163和-0.135,P均﹤0.05)。结论南昌地区男性BMD峰值出现在30~39岁年龄段,而后随年龄增加BMD下降,骨质疏松患病率增加。吸烟是骨质疏松的危险因素,为预防骨质疏松应尽早戒烟。
Objective To investigate the bone mineral density of healthy adult men in Nanchang and to explore the relationship between smoking and bone mineral density. Methods 548 cases of healthy adult male lumbar spine (L2 ~ L4), left femoral neck and left forearm BMD were measured by OSTEOCORE2 dual-energy X-ray absorptiometry in MEDILINK, France. BMD and bone in different age groups Prevalence of quality changes loose. And grouped according to smoking index to analyze the relationship between BMD and smoking index. Results The lumbar spine, femoral neck and forearm BMD peak appeared in the age group of 30-39 years old, then decreased with age, decreased more obviously after 50 years old, and the prevalence of osteoporosis increased with age. The smoking index was negatively correlated with the lumbar spine BMD (r = -0.472, P <0.01), and negatively correlated with the femoral neck and forearm BMD (r = -0.163 and -0.135, respectively, P <0.05). Conclusions The peak value of male BMD in Nanchang appears in the age group of 30-39 years, and then decrease with the increase of age, and the prevalence of osteoporosis increases. Smoking is a risk factor for osteoporosis, smoking should be stopped as soon as possible to prevent osteoporosis.