论文部分内容阅读
Background: In the United States and Europe,about 40-80%of head and neck squamous cell carcinoma are caused by human papillomavirus(HPV).The expression of p16 has been demonstrated to be a favorable biomarker for patients with head and neck squamous cell carcinoma.However,p16 expression and its prognostic value of laryngeal squamous cell carcinoma in Chinese patients are unknown.We aimed to investigate p16 expression and its prognostic value in a large group of Chinese patients with laryngeal squamous cell carcinoma.