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Exploring whether allelochemicals from invasive plants have hormetic dose-response relationships may improve our understanding of the role of allelopathy in plant invasion.We tested the responses of germination, seedling growth and physiological activities of lettuce (Lactuca tatarica Breitung) to the allelochemicals from rhizomes of Solidago canadensisis L.at various concentrations.The hormetic dose-response relationships were tested by using the bioassay data to simulate the mathematically modeling of An_hormesis via nonlinear curve fitting methods through the data analysis and graphing software of OriginLab.We found that germination rote, biomass and physiological activities including superoxide dismutase (SOD),malondialdehyde (MDA), relative electronic conductivity (cellular electrolyte leakage index), and chlorophyll a and b had dose-dependent responses.