Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder

来源 :第四届中国计算蛋白质组学研讨会 | 被引量 : 0次 | 上传用户:wensiuu
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background-Introduction of tyrosine phosphorylation signaling-Enrichment of tyrosine phosphorylation using antibodies Result-Efficient pTyr peptide enrichment by an pTyr superbinder-Tyr phosphoproteome determined by the superbinder
其他文献
Protein structure prediction---from sequence to structure Ways to Obtain Protein Structures Wet lab methods:X-ray and NMR $150k per structure 0.5 year Still nee
会议
文章介绍了最常见的肽鉴定的两个方式以及序列库不准确时的问题。面对不准确或者同源的数据库,进行蛋白质测序时,针对多酶切形成重叠肽序列,应分别测序后拼接,同源搜索,得到同源蛋
文章介绍了华大的生物信息学研究:从新一代测序技术的基因组学到基于质谱仪的蛋白质组学。指出高精准、海量的数据是基础,高效能的大型计算机是保障,自由交流的氛围保证了员工的
  Panicle architecture determines the number of spikelets per panicle and is highly associated with grain yield in rice.Understanding the genetic basis of pan
  The primary aerial surfaces of land plants are coated with a lipidic cuticle,whose cutin polymer matrix and filler waxes form a hydrophobic barrier against
Outline Glycosylation Glycan structure determination Two similar mathematical models Their algorithms and complexities Experiments and Results Post-translationa
会议
  RH(Rathu Heenati),an indica rice cultivar from Sri Lanka,is highly resistant to several different biotypes of brown planthopper(Nilaparvata lugens St(a)l,BP
会议
蛋白质组学是遗传信息、环境因素、生活习惯的多因素的综合体现,最能反映疾病是否发生及发生的进程,可从精准治疗、诊断、预防三个方面助力精准医学计划的开展;Orbitrap超高分辨
针对当前鉴定交联肽段存在的问题,通过借助标记技术、可碎裂交联剂、使用高效搜索技术得以解决。实践证实,pLink2速度提升10到20倍,pLink2交联肽段数目提升50%。
Introduction of cross-linking mass spectrometry(XL-MS) XL-MS workflow Maximal distance constraints Introduction of cross-linking mass spectrometry(XL-MS) Proteo
会议