Future potential of the neuroprotective agent (local application) for the nerve injury in radical pr

来源 :GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会 | 被引量 : 0次 | 上传用户:aiaiai19870310
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Neurogenic erectile dysfunction (ED) resulting from cavernous nerve injury is a major complication caused by radical prostatectomy (RP).Restoration of erectile function with intracavernous injections of platelet-rich plasma (PRP) or endothelial progenitor cells (EPC) after bilateral cavernous nerve injury in rats are studied in our laboratory.In each study, 24 male Sprague-Dawley rats are randomized into three groups: sham surgery, injured control, and PRP or EPC treatment.Injured-control and PRP or EPC treatment groups are subjected to bilateral CN injury before treatment with vehicle or PRP or EPCs injected into the corpora cavernous, respectively.
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