【摘 要】
：
It has been of interest to find guiding principles to help us understand how nanoscale objects interact with living organisms. Firstly, the nanoscale is unique in biology, and our capacity to engineer
【机 构】
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Centre for BioNano Interactions, University College Dublin, Ireland
【出 处】
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The 6th International Conference on Nanoscience and Technolo
论文部分内容阅读
It has been of interest to find guiding principles to help us understand how nanoscale objects interact with living organisms. Firstly, the nanoscale is unique in biology, and our capacity to engineer on that scale is transformative. The intrinsic machinery of biology is defined and operates on the nanoscale. Typical biomolecules and assemblies that are actively transported around organisms by specific motors and drivers are between 5-80nm. This means that nanoparticles are also actively transported around cells and biological barriers all unlike small molecules which passively partition into biological compartments (cells, organs, etc.). Secondly, the power of being able to communicate with, and use those endogenous mechanisms of biology is potentially transformative in practical terms. It is clear, and is often discussed how transformative could be the contribution of nanoscience to medicine, diagnostics, and new kinds of cell therapies.
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