Bovine serum albuminan efficient and green biocatalyst for one-pot four-component reaction for synth

来源 :第五届岭南有机化学论坛暨华南理工大学-兰州大学有机化学双边论坛 | 被引量 : 0次 | 上传用户:sprinia
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The application of biocatalysts in catalysis is attracting more and more attention in the field of chemistry.Bovine serum albumin(BSA),which is a ubiquitous and inexpensive,non-enzymatic transport protein,could serve as an efficient retrievable catalyst in one-pot four-component reaction of aryl aldehydes,malononitrile,hydrazine hydrate,and ethyl acetoacetate for the synthesis of pyrano[2,3-c]pyrazoles under mild reaction conditions.
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