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  5. A magnetic resonance imaging nanosensor for Hg (II) based on thymidine-functionalized supermagnetic

A magnetic resonance imaging nanosensor for Hg (II) based on thymidine-functionalized supermagnetic

来源 :第六届全国低场核磁共振技术与应用研讨会 | 被引量 : 0次 | 上传用户：seuarchi
【摘 要】
：
A MRI nanosensor for Hg (II) was developed based on superparamagnetic iron oxide nanoparticles (SPIO NPs).The detection mechanism is attributed to Hg (II)-induced nanoassembly of thymidinefunctionaliz
【作 者】
：
Hong Yang Zhiqing Tian Juanjuan Wang Shiping Yang 
【机 构】
：
Department of Chemistry,College of Life and Environmental Science,Shanghai Normal University,No. 100
【出 处】
：
第六届全国低场核磁共振技术与应用研讨会
【发表日期】
：
2014年5期
【关键词】
：
MRI nanosensor Hg (II) Thymidine Iron oxide Nanoparticles Transverse relaxation 
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　　A MRI nanosensor for Hg (II) was developed based on superparamagnetic iron oxide nanoparticles (SPIO NPs).The detection mechanism is attributed to Hg (II)-induced nanoassembly of thymidinefunctionalized SPIO NPs from a dispersed to an aggregated state with a corresponding decrease in the transverse relaxation time (T2) of adjacent water protons.Furthermore,an enhancement of transverse relaxation rates (1/T2) showed the high selectivity for Hg (II) compared with other transition and main group metal ions.
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