【摘 要】
：
Toxoplasmosis caused by the protozoan Toxoplasma gondii is a major public health problem,infecting one third of the world human beings,and lead to abortion in domestic animals.A vaccine strategy would
【机 构】
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中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室甘肃省动物寄生虫病重点实验室,兰州 730046
【出 处】
：
中国畜牧兽医学会家畜寄生虫学分会第七次代表大会暨第十二次学术研讨会
论文部分内容阅读
Toxoplasmosis caused by the protozoan Toxoplasma gondii is a major public health problem,infecting one third of the world human beings,and lead to abortion in domestic animals.A vaccine strategy would be ideal tool for improving the disease control.Many efforts have been made on development of vaccines against T.Gon dii to reduce oocyst shedding in cats and tissue cyst formation in mammals over the last 20 years,but only a livEattenuated vaccine based on the S48 strain has been licensed for veterinary use.We here review the recent deve lopment ofT.gondii vaccines in cats,food:producing animals and mice,and present its future perspectives.Ho wever,a single or only a few antigen candidates revealed by various experimental studies are limited by only eliciting partial protective immunity against T.gondii.Future studies ofT.gondii vaccines should include as many CTL epitopes as the live,attenuated vaccines.
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