论文部分内容阅读
目的:通过研究过表达低磷酸化IκB-β的转基因小鼠与野生型小鼠盲肠结扎穿刺(CLP)后脓毒症肺损伤的程度及肺组织炎症细胞趋化情况,来探讨低磷酸化Iκ B-β对小鼠脓毒症肺损伤的保护作用及其是否是通过降低肺组织炎症细胞趋化而起作用.
低磷酸化IκB-β通过减少炎症细胞趋化对小鼠脓毒症肺损伤的保护作用及机制
【摘 要】
：
目的:通过研究过表达低磷酸化IκB-β的转基因小鼠与野生型小鼠盲肠结扎穿刺(CLP)后脓毒症肺损伤的程度及肺组织炎症细胞趋化情况,来探讨低磷酸化Iκ B-β对小鼠脓毒症肺损伤的保护作用及其是否是通过降低肺组织炎症细胞趋化而起作用.
【机 构】
：
第二军医大学附属长海医院全军烧伤研究所
【出 处】
：
全国第二十三届烧伤专业委员会学术会议
【发表日期】
：
2015年4期
其他文献
CAR Knockdown Accelerates HaCaT Cell Migration, Proliferation, and in vivo Wound Healing via Src-p38
Coxsackie and adenovirus receptor (CAR), a cell adhesion molecule of the immunoglobulin superfamily, is predominantly localized to cell-cell contacts between epithelial and endothelial cells.
会议
Double mutation of Src at Tyr407 and FAK at Tyr597 improves collagen arrangement and extracellular m
Hypertrophic scarring (HS) is a serious fibrotic skin condition, there is currently no satisfactory therapy to treat the disease, largely due to the undefined molecular mechanism.
会议
Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resista
Hypertrophic scar (HS) is characterized by the overgrowth of fibroblasts and often considered as a kind of benign skin tumor, thus chemotherapeutic drugs have been used to treat HS.
会议
Loss of CAR promotes the migration and proliferation of HaCaT cells, and accelerates wound healing i
The coxsackie and adenovirus receptor (CAR) is a cell adhesion molecule belonging to the immunoglobulin superfamily and is predominantly localized to cell-cell contacts between epithelial and endothel
会议
Understanding the “barriers” of psychological services for burn injury patients in China: An explora
Introduction Many burn injury patients, claiming the history of psychiatric disorders, do not meet sufficient mental health care.These problems are more serious in China, which is a developing country
会议
Recovery of lost face for burn patients, their perceived changes and coping strategies in the rehabi
Background: Although burn injury remains one of the most devastating ordeals for the human being, little has been reported on the individual patients perception about the burn experience in the Chines
会议
Purpose:Multipotent mesenchymal stromal cells, often labeled mesenchymal stem cells (MSCs) are considered a highly promising candidate cell type for cell-based tissue engineering and regeneration beca
会议
Allogeneic organ transplantation has become a common and final clinical treatment for organ failure.
会议
目的 初步验证吲哚胺2,3-双加氧酶(IDO)在BMSCs对初始CD4+T细胞向Th 17/Treg细胞分化的影响及其可能机制.方法 分离培养Balb/c小鼠来源的BMSCs,以Balb/c小鼠脾脏来源的CD4+T细胞为反应细胞,以丝裂霉素预处理过的C57BL/6小鼠脾脏细胞作为刺激细胞.实验分为3组：对照组,刺激细胞+反应细胞；BMSCs组,刺激细胞+反应细胞+BMSCs；IDO拮抗组,刺激细胞
The effects and mechanism of miR155 on thefibroblasts-to-myofibroblasts transition in dermal fibrobl
Hypertrophic scar, which is a troublesome problem in the field of tissue repairthat urgently need to be solved.Present study confirmed that TGF-β 1 inducedmyofibroblasts transition is the key mechanis