Drosophila Wingless (Wg) is a secreted protein which forms the concentration gradient to determine cell fates during the development of multicellular organisms.Wg signaling and distribution are controlled by various components, one of which is Dally-like (Dlp), a heparan sulfate proteoglycans (HSPGs).Recent studies show that Dlp assists Notum deacylating Wg as a scaffold.