【摘 要】
:
Lipid droplets (LDs) are the organelles responsible for lipids storage.The sizes of LDs vary greatly under different physiological conditions.Comprehensive studies show that LDs size is important for
【机 构】
:
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101,China
【出 处】
:
The 2016 International Conference on Lipid Metabolism and Bi
论文部分内容阅读
Lipid droplets (LDs) are the organelles responsible for lipids storage.The sizes of LDs vary greatly under different physiological conditions.Comprehensive studies show that LDs size is important for LDs function,however the mechanism underlying LDs size regulation remains poorly understood.
其他文献
Long non-coding RNAs (lncRNAs) have been shown to be critical biomarkers or therapeutic targets for human diseases.However,only a small number of lncRNAs were screened and characterized.
Whole-body energy metabolism and cardiovascular homeostasis are tightly controlled processes that involve highly coordinated crosstalk among distal organs.This is mainly achieved by a large number of
Brain plays an important role in regulating energy balance and glucose hemeostasis.There have two key anti-obesity neurocircuitry pathways in the brain.The first pathway is the serotonin 2C receptor (
GH/IGF-Ⅰ axis is a conservatory signalling pathway that serves as a primary and pivotal regulator of postnatal growth,glucose,lipid and protein metabolism,which are widely associated with cancer,aging
Vascular endothelial cell growth factor (VEGF) family includes VEGF-A,VEGF-B,VEGF-C,VEGF-D,VEGF-E and placental growth factor (P1GF).VEGF-A is an essential growth factor for angiogenesis and adipose s
Endoplasmic Reticulum (ER) stress response,namely the Unfolded Protein Response (UPR),is known to be crucial for cells to make survival or death decision under acute stress conditions.However,the role
CD8+ T cells have a central role in antitumor immunity,but their activity is suppressed in the tumor microenvironment.Reactivating the cytotoxicity of CD8+ T cells is of great clinical interest in can
The dysfunction of adipose tissue plays an important role in metabolic disorders.Adipose inflammation is involved in the pathogenesis of diet-induced adipose dysfunction.Adipose innate immunological r
Insulin resistance is a hallmark in the development of type 2 diabetes mellitus (T2DM),which is associated with obesity.A considerable number of recentstudies have pointed out a critical role of endop
Fluoxetine (FLX),a typical drug belonging to the category of selective serotonin reuptake inhibitors (SSRI),is the most widely prescribed psychoactive drug in the treatment of depression and other moo