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5. Translational regulation of DNA repair systems by elF3a in cancer chemotherapeutic response

Translational regulation of DNA repair systems by elF3a in cancer chemotherapeutic response

来源 :中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛 | 被引量 : 0次 | 上传用户：iamup

【摘 要】

：

OBJECTIVE To investigate the role of elF3a in the regulation of DNA repair pathways in cancer chemotherapeutic response.METHODS Immunohistochemistry was used to determine the expression of elF3a in lu

【作 者】

：

CHEN Juan CUI Jia-jia ZHANG Jian-ting ZHOU Hong-hao LIU Zhao-qian YIN Ji-ye 

【机 构】

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Department of Clinical Pharmacology, Xiangya Hospital,Central South University, Changsha 410008, Chi

【出 处】

：

中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛

【发表日期】

：

2016年11期

【关键词】

：

elF3a DNA repair translation regulation platinum anthracycline cancer chemothera 

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　　OBJECTIVE To investigate the role of elF3a in the regulation of DNA repair pathways in cancer chemotherapeutic response.METHODS Immunohistochemistry was used to determine the expression of elF3a in lung and breast cancer tissues followed by association analysis of elF3a expression with patients response to chemotherapy.

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