Enhanced scratching elicited by a pruritogen and an algogen in a mouse model of contact hypersensiti

来源 :中国药理学会北美分会药理学学术大会 | 被引量 : 0次 | 上传用户:linxunchang
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Chemical pruritogens and algogens evoke primarily itch and pain,respectively,when administered to the skin of healthy human subjects.However,the dominant sensory quality elicited by an algesic chemical stimulus may change in patients with chronic itch where bradykinin,elicits itch in addition to pain.
其他文献
  Firing activity of pacemaker cells underlies an array of fundamental physiological processes,such as heartbeat and respiration.Key to the generation of spon
会议
  The endogenous signaling gasotransmitter hydrosulfide(H2S)can exert cardioprotective effects in acute myocardial ischemic(AMI)injury.
会议
  As an optimal solution for patients with end stage cardiac failure,heart transplantation has been applied in clinic for decades.
会议
  Here we investigated the effects and the underlying mechanism of Ginkgolide K(1,10-dihydroxy-3,14-didehydroginkgolide,GK)on cardiac ER stress.
会议
  Ca2+-activated Cl- channels play a crucial role in various physiological processes.However,the role of TMEM16A in vascular endothelial dysfunction during hy
会议
会议
  The narrow therapeutic window of warfarin makes itself the most common drug involved in drug/herb-drug interaction,which often causes safety concerns,primar
会议
  Hypotonic challenge evoked vascular cell proliferation through activation of volume-regulated Cl-channel(VRCC),leading to the decline of intracellular Clcon
会议
会议
  Recent evidence suggested that ClC-3,encoding Cl-channel or Cl-/H+antiporter,plays a critical role in regulation of a variety of physiological functions.
会议