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  5. Polyethyleneglycol Based Nanoparticles:Design Synthesisand Bioligical Evaluatuion

Polyethyleneglycol Based Nanoparticles:Design Synthesisand Bioligical Evaluatuion

来源 :中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户：charoltte8816
【摘 要】
：
PEG,(poly(ethylene glycol),is the gold standard biocompatible polymer with good water solubility and is classified as Generally Regarded as Safe(GRAS)by the FDA.PEGylation has been as general pattern
【作 者】
：
Jie Pang Shiyong Zhang 
【机 构】
：
National Engineering Research Center for Biomaterials,Sichuan University,29 Wangjiang Road,Chengdu 6
【出 处】
：
中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议
【发表日期】
：
2016年5期
【关键词】
：
PEG conformation tumor 
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　　PEG,(poly(ethylene glycol),is the gold standard biocompatible polymer with good water solubility and is classified as Generally Regarded as Safe(GRAS)by the FDA.PEGylation has been as general pattern in the design of drug delivery system,but few reports used the PEG as the main body structure since the good dispersibility of PEG in the water.PEG is well dissolved in water with trans-gauche-trans conformation,and it aggregates with trans-trans-trans conformation in the water when it is heated and on other conditions(1,2).
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