论文部分内容阅读
PIWI proteins are known to enlist germline-specific Piwi-interacting RNAs(piRNAs)to suppress transposable elements and protect the integrity of the genome in germ cells.Our recent studies showed that mouse PIWI(MIWI)interacts to APC/C E3 complex and is ubiquitinated by APC/C in late spermatids(Zhao et al.,Dev Cell 2013,24:13–25).