Hypertrophic cardiomyopathy (HC) is a hereditary myocardial disorder, caused by mutations of sarcomeric proteins.25% of cases of HC there is associated obstruction to left ventricular (LV) outflow.Obstruction can occur at several locations within the ventricle, depending on the distribution of hypertrophy.Patients with obstruction are often symptomatic from hemodynamic causes.Non-surgical treatment options for the obstructive cardiomyopathies are performed to increasing number of patients to reduce hospitalization duration and cost.During the past 10 years, atrio-ventricular sequential pacing and alcohol septal ablation have been proposed as less invasive alternatives to surgery for patients who fail to respond to pharmacologic therapy.However, atrioventricular sequential pacing is not currently thought to be dramatically beneficial.