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Objective To investigate the optimal reconstruction technique after proximal gastrectomy.in the Treatment of Esophagogastric Junction Cancer.Methods: A total of 110 patients with Esophagogastric Junction Cancer undergoing proximal gastrectomy in Sichuan Cancer Hospital between January 2010 and December 2011 were divided into 3 groups according to the reconstruction technique: group A (Remnant stomach modified Roux-en-Y esophagojejunostomy, n=37), group B (Roux-en-Y esophagojejunostomy , n=37), group C (esophagogastrostomy, n=36).Operation time, quality of life (QOL), nutritional status 1 year after surgery, and perioperative complications were analyzed.Results: There were no significant differences in Operation time and perioperative complications (P>0.05).One year after operation, QOL (Visick index) was better in group A than that in group B and C (P<0.05).The increase weight gain, in food intake, albumin were better in group A than those in group B and C (P <0.05).The prognostic nutrition index ratio of group A was better than that in group B and C.The incidences of dunping syndrome, reflux esophagitis, in group A were significantly lower than those in group B and C (P<0.05).Conclusions: Remnant stomach modified Roux-en-Y esophagojejunostomy which prevents the reflux esophagitis and dumping syndrome, preserves the pathway of duodenum and promotes, is associated with improved nutritional condition and quality of life.It is a reasonable reconstruction method after proximal gastrectomy.