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Introduction Muscle tissue is the largest tissue in the body and it may directly influence whole body growth.Muscle growth is regulated by the myostatin gene (MSTN).In chicken the correlation between the expression of the myostatin gene and growth rate, muscle mass, and body weight remains poorly investigated.We used the Wuding chicken and the Avian broiler chicken as a model system to investigate the correlation.Wuding chicken is a local chicken breed and growth slowly.