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  5. A high performance deep tumor penetration nanocarrier via overcoming both tumor extracellular matrix

A high performance deep tumor penetration nanocarrier via overcoming both tumor extracellular matrix

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：sunday826
【摘 要】
：
　　The physiological barriers of tumor itself are main challenges that blunt the non-surgical treatment of malignant solid tumors [1,2].The tumor extravascular
【作 者】
：
YangWang;HuileGao;QinHe; 
【机 构】
：
Key Laboratory of Drug Targeting and Drug Delivery Systems,West China School of Pharmacy,Sichuan Uni
【出 处】
：
The 6th International Conference on Nanoscience and Technolo
【发表日期】
：
2015年期
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　　The physiological barriers of tumor itself are main challenges that blunt the non-surgical treatment of malignant solid tumors [1,2].The tumor extravascular barrier(TEVB)composed of tumor extracellular matrix(ECM)and multiple layers of tumor cells(MLTC)is the most formidable one [3].Based on this consideration,we reported herein a core-shell and size multistage changeable nanocarrier that could overcome the double barriers from ECM and MLTC.
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