【摘 要】
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A growing body of evidence suggests that the endogenous ligand of NPSR,NPS,could promote arousal and anxiolytic-like effects[1-3].The predominant distributi
【机 构】
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Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences
论文部分内容阅读
A growing body of evidence suggests that the endogenous ligand of NPSR,NPS,could promote arousal and anxiolytic-like effects[1-3].The predominant distribution of NPSR in brain tissues involved in learning and memory,NPS has been showed to modulate cognitive function in rodents[4-6].In present study,we investigated the function of NPS in memory formation,and examined whether NPS could alleviate memory impairment induced by selective N-methyl-D-aspartate receptor antagonist MK801,muscarinic cholinergic receptor antagonist scopolamine or Aβ1-42 in mice,using novel object recognition tasks.
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