小鼠肺间质纤维化中,CD147促进M1型巨噬细胞亚型诱导Th17细胞分化

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：pgq1989

【摘要】

：

研究背景:肺间质纤维化是一种慢性的、渐进的肺间质疾病,其特点是大量积累细胞外基质,重塑肺结构,并伴随着严重的关节炎等并发症.在肺间质纤维化发生发展过程中,巨噬细胞、Th17细胞及一些其他淋巴细胞都起到非常关键的作用.研究表明,在人或鼠的肺纤维化过程中,CD147的表达会上升,但是CD147在肺纤维化中的具体作用机制还不清楚.

【作者】

：

耿杰杰

【机构】

：

第四军医大学

【出处】

：

中国免疫学会第九届全国免疫学学术大会

【发表日期】

：

2014年8期

【关键词】

：

M1、M2巨噬细胞小鼠肺间质纤维化 Th17细胞 CD147

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小鼠肺间质纤维化中,CD147促进M1型巨噬细胞亚型诱导Th17细胞分化

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