Metal-Free 2,3-Dihydroisoxazoles Synthesis using Nitrones and Alkynes under Mild Conditions

来源 :中部四省化学化工学会2017年学术年会 | 被引量 : 0次 | 上传用户：daiap

【摘要】

：

　　An elegant and efficient synthesis of 2,3-dihydroisoxazoles from the reactions of nitrones with alkynes was developed.In the presence of base Na2CO3,regiose

【作者】

：

赵森陈荣星汪刚强陈秀玲孙绍发

【机构】

：

湖北科技学院核技术与化学生物学院,湖北省咸宁市咸宁大号88号,437100

【出处】

：

中部四省化学化工学会2017年学术年会

【发表日期】

：

2017年10期

【关键词】

：

Base-catalyzed [3+2]-cycloaddition nitrones alkynes 2 3-Dihydroisoxazoles

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　　An elegant and efficient synthesis of 2,3-dihydroisoxazoles from the reactions of nitrones with alkynes was developed.In the presence of base Na2CO3,regioselective [3+2]-cycloaddition of nitrones and alkynes was achieved under metal-free condition.This [3+2]-cycloaddition process is compatible with a wide range of substrates.

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Metal-Free 2,3-Dihydroisoxazoles Synthesis using Nitrones and Alkynes under Mild Conditions

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