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  5. Dual-functional LT-loaded reconstituted HDL designed based on median-effect principle for synergisti

Dual-functional LT-loaded reconstituted HDL designed based on median-effect principle for synergisti

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：jiahong222
【摘 要】
：
Reconstituted high density lipoprotein (rHDL) displays dual functions in plaque targeting and anti-atherosclerosis.In our previous studies,cardiovascular drug tanshinone ⅡA (TA)-loaded rHDLs were prov
【作 者】
：
Cuiping Jiang Yi Zhao Yun Yang Mengyuan Zhang Jianhua He Jing Lu Wenli Zhang Jianping Liu 
【机 构】
：
Department of Pharmaceutics,China Pharmaceutical University,Nanjing 210009,China
【出 处】
：
Fourth Symposium on Innovative Polymers for Controlled Deliv
【发表日期】
：
2016年11期
【关键词】
：
high density lipoprotein atherosclerotic targeting drug combination median-effec 
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　　Reconstituted high density lipoprotein (rHDL) displays dual functions in plaque targeting and anti-atherosclerosis.In our previous studies,cardiovascular drug tanshinone ⅡA (TA)-loaded rHDLs were proved to have stronger antiatherogenic efficacies and better plaque targeting properties than conventional TA-loaded lipid nanocarriers in atherosclerotic rabbits[1-2].
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