Targeting delivery of PCL-PEG nanomicelles with low-dose dexamethasone for reduced side effects in r

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户:liongliong549
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Glucocorticoids (GC) have been considered as the cornerstone for the therapy of for rheumatoid arthritis decades.However, the systemic application is limited because of a high incidence of serious adverse effects which are strongly dose dependent.
其他文献
Chemotherapy is a crucial measure in the comprehensive strategies in treatment of breast cancer, but the regular chemotherapy seemed to be less efficient in controlling the continued development of br
Submicron emulsions (SEs) is an advanced formulation that possesses good biocompatibility, high loading of hydrophobic drugs, and good stability through autoclave sterilization.To enhance tumor target
Nanomedicines are appealing increasing attention because of their excellent performances, such as flexibility, biocompatibility and selectivity, which make the combination of therapy and diagnosis pos
会议
Mesoporous silica nanoparticles (MSNs) exhibit a uniform pore distribution , high specific surface area, good thermal and hydrothermal stabilities, the unique characteristics of tunable pore sizes,hig
Objective: To prepare UCNP-Ce6 hybrids and investigate its upconversion luminescence imaging and MRI dual-modal imaging properties as well as its in vitro/in vivo photodynamic therapy of tumor effects
Active targeting drug delivery system is an effective strategy in cancer therapy currently, and among all the methods, peptide-mediated targeting of tumors has attracted researchers attention.We used
会议
Mesenchymal stem cells (MSCs) have been extensively investigated to treat a wide range of diseases due to their easy accessibility, high self-renewal capacity, low immunogenicity, and free of ethical
In this study, a purified polysaccharide was extracted and isolated from the fruitbodies of Lentinus edodes, and its anti-tumour effect and apoptosis-inducing activity in S 180 tumour bearing mice has
会议
Elacridar (ELC), a reversal agent of multidrug resistance (MDR), has been demonstrated as an excellent P-glycoprotein (P-gp) inhibitor which could reverse P-gp mediated drug efflux[1].However, low sol
Objective: To increase targeting effect and reverse the multiple drug resistance(MDR) on cancer cells by building and investigating a pH and reducibility dual-sensitive "binary polymer" that Low densi