Cholangiocytes are the targets of cholangiopathies, including primary sclerosing cholangitis (PSC) that are identified by dysregulation of cholangiocyte prolife
Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease in industrialized countries with limited therapeutic options.
Background and Aim: Recently,the usesfulness of endoscopic submucosal tunnel dissection(ESTD)in the management of upper gastrointestinal submucosal tumors(S
大肠癌流行病学全球:发病率第4,病死人数第4(2012年)我国:发病率第3,病死人数第5(2008年)2012年全世界癌死亡820万(占因病而亡人数的13%)
Fibroblast growth factor 15 (FGF15, human homologue, FGF19) is one of the endocrine FGFs that are critical in suppressing bile acid synthesis and promoting prot
Many metabolic enzymes such as cytochrome P450s (CYPs) and aldehyde and alcohol dehydrogenases (ALDHs, ADHs) are important in the regulation of the concentratio
Central and sympathetic nervous systems govern functional activities of many organs.Solid tumors like organs are innervated by sympathetic nerve fibers.Neur
Cell ablation is a powerful tool for studying cell lineage and/or function; however, current cell-ablation models have limitations.
Cytochrome P450 (P450) enzymes play a critical role in metabolism of xenobiotics, including drugs and toxicants. Control of P450 expression can directly influen
传统观点认为癌是局部组织中细胞自主性异常生长,因此长期以来,对癌症的基础研究大多局限在"癌细胞"层面.机体对癌的系统性调控,尤其是神经和神经递质在其中所起的作用,尚不