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Perineuronal nets(PNs)are implicated in controlling neural plasticity during neuronal circuit formation in the postnatal CNS.With negative geotaxis as a readout of postnatal maturation of the vestibular-motor circuit,we found emergence of the behavior in correlation with consolidation of PN around GABAergic/parvalbumin-positive interneurons in the vestibular nucleus(VN)of rats by P9.