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5. Innovative co-delivery system of siRNA and Doxorubicin aimed to reversal multidrug resistance via su

Innovative co-delivery system of siRNA and Doxorubicin aimed to reversal multidrug resistance via su

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：jianting520

【摘 要】

：

P-glycoprotein(P-gp)plays an importantrole in multi-drug resistance(MDR),proved to be one of the major obstacles in cancerchemotherapy.Cationic polymerscould specifically deliver siRNA to tumor cells

【作 者】

：

Shu-di Yang Chun-ge Zhang Xue-nong Zhang 

【机 构】

：

Department of Pharmaceutics,College of Pharmaceutical Science,Soochow University,Suzhou 215123,Peopl

【出 处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

【关键词】

：

cationic triblock copolymer siRNA multidrug resistance micelle 

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　　P-glycoprotein(P-gp)plays an importantrole in multi-drug resistance(MDR),proved to be one of the major obstacles in cancerchemotherapy.Cationic polymerscould specifically deliver siRNA to tumor cells and thus reverse MDR by down-regulation ofP-gp.

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