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Recent years,surface enhanced Raman scattering(SERS)have attracted tremendous attentions for label-free,sensitive,specific detection.An ideal SERS spectrum would be collected from substrates containing lots of "hot-spot" to enhance surface plasma resonance,and higher concentration of target molecules.Many teams have reported efficient SERS substrates with abundant "hot-spot" fabricated by chemical/physics etching,deposition,or self-assembly,but they failed to gather the scarce target molecules for higher concentration and then higher intensity of SERS spectrum.