论文部分内容阅读
Our efforts on the development of colloidal photoluminescent (PL) quantum dots (QDs),such as CdTeSe/CdS as near-infrared emitters,and CdSe/ZnS and CuInS2/ZnS as red emitters will be addressed in this presentation,together with their single-domain antibody (sdAb) bio-conjugates for in vitro and in vivo cancer imaging.The development background on the colloidal PL QDs and state of the art will be introduced,such as QD blinking.More importantly,I will introduce our long lasting efforts on developing various synthetic approaches to various colloidal (PL) nanocrystals (NCs also called QDs),including regular nanocrystals (RNCs),magic-sized nuclei (MSN),and magic-sized clusters (MSCs).The growth patterns and optical properties of these NCs will be presented,together with our latest understanding on the formation of monomers leading to nucleation/growth of the different groups of NCs.Regarding the bio-oriented application,the RNCs are preferred at present,and the synthesis-composition/structure-property relationship will be discussed for these RNCs.Although PL RNCs exhibiting bandgap emission in the near-infrared wavelength of the electromagnetic spectrum seem to have significant potential in bio-related applications,their synthesis with controlled optical properties including bandwidth and peak position as well as their characterization still remain challenging.Briefly,both hot-injection and noninjection approaches will be addressed,together with the comparison of the optical properties of the CdTeSe QDs developed from our laboratories and other laboratories.Solid-state Nuclear Magnetic Resonance (NMR) as a powerful tool for the structural determination of homogeneous or gradient alloyed QDs will be introduced.This presentation aims at breeding thoughts on what the next step should be to move one step forward for the QD potential in the bio-oriented applications,with the introduction on synthesisstructure- property-application relationships.