Long non-coding RNA IRAIN suppresses apoptosis and promotes proliferation by binding to LSD1, EZH2 i

来源 :第19次全国干扰素与细胞因子学术会议 | 被引量 : 0次 | 上传用户：winwo408

【摘要】

：

【作者】

：

Yifan Lian Jing Feng Keming Wang

【机构】

：

Department of 0ncology, Second Affiliated Hospital, Nanjing Medical University, Nanjing,210000, J

【出处】

：

第19次全国干扰素与细胞因子学术会议

【发表日期】

：

2016年10期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Long non-coding RNA (lncRNA) modulate gene expression,and lncRNA dysregulation is associated with human cancer disease.Recent studies have shown that lncRNA IRAIN plays an important role in other malignancies,yet the role of IRAIN involved in pancreatic cancer (PC) progression remains unclear.

其他文献

截断与模拟磷酸化Par-4抗肿瘤的作用及机制

目的：研究截断与模拟磷酸化Par-4对前列腺癌细胞的影响和其抗肿瘤的作用及机制。方法：(1)化学合成获得SAC-wt,SAC-T163D和SAC-T163A的大肠杆菌偏爱的编码序列,分别插入pMAL-c5x,构建成表达质粒。(2)将(1)中构建的质粒转入大肠杆菌BL21,分别以IPTG诱导表达。(3)通过SDS-PAGE和Westernblot鉴定三种重组蛋白。(4)麦芽糖亲和纯化得到目的蛋白。(

会议

前列腺凋亡反应蛋白-4模拟磷酸化抗肿瘤

重组人白介素2的长效化及靶向化改造及相关药效学和药代动力学的研究

会议

The Long Noncoding RNA BANCR affect the proliferation of CRC cells via downregualtion of p21 Express

BRAF activated non-coding RNA (BANCR),a long non-coding RNA (lncRNA),is crucial for cell migration in melanoma cells and non-small cell lung cancer(NSCLC) cells.However,little is known about the roles

会议

The Long Noncoding RNA BANCRproliferationCRCp21

The long noncoding RNA HOXA transcript at the distal tip promotes colorectal cancer growth partially

Disregulation of long noncoding RNAs (lncRNAs) associated with human carcinogenesis.lncRNA HOXA transcript at the distal tip (HOTTIP) involves in multiple cancers development.

会议

Long non-coding RNA Loc554202 induces apoptosis in colorectal cancer cells via the caspase cleavage

Objective: Colorectal cancer (CRC),as the third most common cancer affecting the gastrointestinal tract,is a common type of cancer worldwide,and is associated with a high mortality rate due to its rap

会议

Long non-coding RNA Loc554202apoptosiscolorectal cancer

The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregul

会议

The long noncoding RNA SPRY4-IT1breast cancerZNF703

RMP通过NF-κ B/CSN2/Snai1通路促进肝癌细胞的上皮间质转化

会议

Long non-coding RNA FOXP4-AS1 is an unfavorable prognostic factor and regulates proliferation and ap

Objectives: Despite improvements in diagnostics and treatment of colorectal cancer (CRC),it remains the third most common malignancy and the fourth most frequent cause of cancer-related deaths worldwi

会议

lncRNAFOXP4-AS1colorectal cancerTNM stageproliferationapoptosis

去泛素化酶Ataxin3促进干扰素抗病毒效应及其机制研究

会议

Long Noncoding RNA HOXA-AS2 promotes colorectal cancer proliferation by recruiting EZH2/LSD1 and rep

Long noncoding RNAs (lncRNAs) have received increased attention as a new class of functional regulators involved in human carcinogenesis.HOXA cluster antisense RNA 2 (HOXA-AS2)is a 1048-bp lncRNA loca

会议

Colorectal cancerHOXA-AS2EZH2LSD1p21

Long non-coding RNA IRAIN suppresses apoptosis and promotes proliferation by binding to LSD1, EZH2 i

与本文相关的学术论文