Objective:To study the clinical value of Advanced prospective ECG-triggering high pitch dual-source computed tomography(FLASH-DSCT) used lower contrast agent in the diagnosis of children with congenital heart disease(CHD) compared with regular postspective ECG-trigger MDCT angiography. Method:Group A:39 patients(age range from 1 months to 10 years ) underwent FLASH-DSCT used 0.75ml/kg contrast agents ; Group B: 47 patients(age range from 1 months to 10 years ) underwent FLASH-DSCT used 1.5ml/kg contrast agents. Group C:42 patients(age range from 1 months to 10 years ) underwent regular MDCT used 1.5ml/kg contrast agents. The CTDI and DLP data of three groups were taken. And recorded overall effective radiation dose(ED). The overall imaging quality was evaluated by a five-point scale, and the results of score was evaluated by t text; However, the Kappa text was for the valuation of consistency . All of the film was diagnosed by two experienced radiologist all alone. The accuracy was calculated based on the surgical or Digital Substraction Angiography (DSA). Results:the mean dose of group A was 0.236mSv, range from 0.06 to 0.412mSv,had significant difference with group C(mean dose 1.898mSv). Close inter observer agreement was found for image quality scores (k = 0.85). The image quality was slightly better of the group A than group C (4.1 vs 3.7, P=0.076). The diagnostic accuracy was similar(group A96.6%,group C 97.5%).The artifacts in Superior vena cava or inferior vena cava caused by iodinated contrast agent was almost disappeared in group A. Conclusion:High-pitch prospective ECG-trigger Dual-Source CT angiography can effectively lower radiation dose for the children with CHD while using lower contrast agents , promote the imaging quality, which has significantly clinical value.