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Takayasu arteritis(TA)is a chronic large-vessel vasculitis of unclear pathogenesis.Recently genomewide association study(GWAS)has revealed that the genes FCGR2A/FCGR3A、EEFSEC、RPS9/LILRB3、RIPPLY2 and MLX conferred susceptibility to TA.We investigated the linkage between presumptive TA-related genes(FCGR2A/FCGR3A、EEFSEC、RPS9/LILRB3、RIPPLY2 and MLX)and TA in a Han Chinese population.We performed a large case-control multi-center study of 412 Han Chinese patients with TA and 597 ethnically matched healthy controls.