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Cerebral aspergillosis is a rare complication of multiple trauma.In this report,we present aremarkable case of multiple lung and brain lesions caused by aspergillosis after a falling incident.A 54-year-old male was admitted with multiple trauma (brain contusion; aspiration pneumonitis with pulmonary contusion; right humerus fracture and right scapular fracture) due to a 6-meter-high fall and aspiration of slops.