【摘 要】
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The aggravating trend of aging population has bring us with great medical challenges.Renal senescence related disease continues to be of critical importance
【机 构】
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MOE Key Laboratory of Protein Sciences,Department of Pharmacology,School of Medicine,Tsinghua Univer
【出 处】
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2014 International Conference on Aging and Disease(2014年第一届衰
论文部分内容阅读
The aggravating trend of aging population has bring us with great medical challenges.Renal senescence related disease continues to be of critical importance for its high morbidity rates and huge cost of treatment.Calorie restriction (CR) has various beneficial effects on health, including lifespan prolongation and functional improvement of multiple organisms.SIRT6, a member of the sirtuins family of NAD+-dependent histone deacetylases, has been shown to play a key role in mediating the effects of CR.
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