【摘 要】
:
The aggravating trend of aging population has bring us with great medical challenges.Renal senescence related disease continues to be of critical importance
【机 构】
:
MOE Key Laboratory of Protein Sciences,Department of Pharmacology,School of Medicine,Tsinghua Univer
【出 处】
:
2014 International Conference on Aging and Disease(2014年第一届衰
论文部分内容阅读
The aggravating trend of aging population has bring us with great medical challenges.Renal senescence related disease continues to be of critical importance for its high morbidity rates and huge cost of treatment.Calorie restriction (CR) has various beneficial effects on health, including lifespan prolongation and functional improvement of multiple organisms.SIRT6, a member of the sirtuins family of NAD+-dependent histone deacetylases, has been shown to play a key role in mediating the effects of CR.
其他文献
Age-related chronic persistent low-grade pro-inflammatory state, termed inflamm-aging, is attributed to senescence-associated secretory phenotype (SASP) and
在我国社会发展新形势下,社区在城市化进程的重要性日益凸显,档案管理作为社区工作的关键组成部分,其涉及社会维稳、社区建设以及居民保障等多个方面,对推动城市发展和提升居
请下载后查看,本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.
古籍是我国传统文化和民族智慧的结晶,是古人留给我们的精神财富,对于中华文化的传承起到了极为重要的作用.目前,有大量的古籍被存放在公共图书馆中,供人们参观、浏览,在这个
Thymic epithelial cells (TECs) are a key cell type in thymic microenvironment essential for T cell development.However, intrinsic molecular mechanisms contr
我以前常常从我家厨房的窗户看到她,她强行挤过操场上的一群男孩子,对这些男孩们来说,她显得那么矮小。学校在我家的街对面,我经常看到孩子们在下课时间玩耍。尽管有一大群的
Healthy aging individuals are more likely to suffer profound memory impairments following an immune challenge than are younger adults.These challenges produ
营商环境是运营商贸的核心内容,不仅可以提高运营商贸的规范性,还可以有效促进运营商贸的改革和发展,对于经济增长具有至关重要的意义.当前,“放管服”作为主旋律关键词之一,
高效地进行档案管理工作是事业单位所必需的.随着科学技术和信息水平的不断提高,传统的档案管理方式已经不适应时代的要求,需要将档案管理工作的方式进行优化,已符合时代的标
Age-related hearing loss (ARHL) is a predominant neurodegenerative disease with age.Here, we demonstrate for the first time that, in the aging process, the