【摘 要】
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Objective: Incontinence of urine is related with the pathological process of many brain diseases.The aim of this study was to identify cerebral activation areas during withholding urine in healthy sub
【机 构】
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Department of Nuclear Medicine,the First Hospital of China Medical University,Shenyang 110001,China
【出 处】
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The 1st Sino-American Conference on Nuclear Medicine(首届中美核医学
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Objective: Incontinence of urine is related with the pathological process of many brain diseases.The aim of this study was to identify cerebral activation areas during withholding urine in healthy subjects by SPECT cerebral perfusion imaging.Methods: Sixteen healthy volunteers (mean age 46 years old) were recruited.All had two brain perfusion SPECT scans: resting state with empty bladder and urine withholding state with full bladder.The images were analyzed by Statistical Parametric Mapping (SPM) and displayed at a significant statistical threshold of P<0.05 with correction for multiple comparisons.Results: At the urine withholding state, significant increases of cerebral perfusion in the right parietal lobe, the bilateral superior frontal guri, the right inferior frontal gyri, the right superior temporal gyri and the left claustrum were found.Conclusions: The control of urinary continence in healthy adults was associated with the right parietal lobe, the bilateral superior frontal guri and the right inferior frontal gyri.Moreover, the combination of brain perfusion SPECT and SPM was a convenience, shortcut method to align the functional areas of the brain.
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