Functional Magnetic Nanoparticles for Circulating Tumor Cells Screening in Integrated Microfluidic S

来源 :2014年上海市研究生学术论坛:生物医疗仪器 | 被引量 : 0次 | 上传用户:degr5
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  Screening and analysis of circulating tumor cells(CTCs)can potentially provide crucial information for clinical prevention,diagnosisand treatment of cancer metastasis.Herein we designed variousfunctional magnetic nanoparticles(NPs)to captureCTCs,with further optimization towards rare cell separation with high specificity from the whole blood.In Vitro characterizations were carried out using an integrated microfluidic system coupled with the immunomagnetic assays on-chip towards efficient screening of CTCs in blood samples with high sensitivity.
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