【摘 要】
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Innate antiviral response is critical for host defense against viral infections.Pattern recognition receptors (PRRs) of host cell, such as RIG-like receptor
【出 处】
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中国细胞生物学学会2015年全国学术大会
论文部分内容阅读
Innate antiviral response is critical for host defense against viral infections.Pattern recognition receptors (PRRs) of host cell, such as RIG-like receptors (RLRs), can sense viral PAMPs to initiate and sequentially activate the adaptors, kinases, and IRF and NF-κB family transcriptional factors, leading to synthesis of antiviral transcriptomes including interferons (IFNs), proinflammatory cytokinses, and variety of ISGs.
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